Maintenance hemodialysis
Conditions
Interventions
1:Glucose-containing dialysate for HD
2:Glucose-free dialysate for HD
Sponsors
West China Hospital of Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) Age between 18 and 75 years; (2) Having undergoing maintenance HD three times a week for at least three months and the dialysis mode is relatively fixed; (3) Kt/v = 1.2 in the first 8 weeks before entering the study; (4) Written informed consent provided by the patient or a person with decisional responsibility.
Exclusion criteria
Exclusion criteria: (1) Participants with life expectancy less than 1 year; (2) Participants hospitalized due to decompensation or any other complications of diabetes; (3) Participants under active infection; (4) Pregnancy or nursing, or impending miscarriage; and (5) Participation in another clinical intervention trial within the last 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of the major cardiovascular and cerebrovascular adverse events; | — |
Secondary
| Measure | Time frame |
|---|---|
| All-cause mortality at 1year, 2 years and 3 years follow-ups;The incidence of intradialytic hypotension;The incidence of hypoglycemia;Blood pressure variability during HD;Blood glucose variability during HD;Dysfunction of vascular access;Cardiac function;Fatigue level; | — |
Countries
China
Contacts
Public ContactZhang Ling
West China Hospital of Sichuan University
Outcome results
None listed