inflammatory bowel disease
Conditions
Interventions
Sponsors
West China Hospital of Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Inclusion criteria for IBD patients 1) Patients who meet the diagnostic criteria for Consensus on the diagnosis and treatment of inflammatory bowel disease in China (2018 Beijing). Combined analysis of clinical manifestations, laboratory examination results, endoscopic findings, histopathological and imaging evidence; 2) Age over 18 years old and with capacity for civil acts. 2. Inclusion criteria for healthy controls 1) Healthy volunteers; 2) Age over 18 years old and with capacity for civil acts.
Exclusion criteria
Exclusion criteria: 1. Exclusion criteria for IBD patients 1) Used antibiotics in recent four weeks; 2) With uncontrolled infections or sepsis; 3) With rheumatic diseases, hepatitis, intestinal tuberculosis and malignant tumor. 2. Exclusion criteria for healthy controls 1) Used antibiotics in recent four weeks; 2) With constipation, abdominal pain, diarrhea, abdominal discomfort, or changes in stool characteristics in four weeks before collecting specimens; 3) History of abdominal or intestinal surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the GPR15 levels in peripheral blood;the GPR15 levels in colonic specimens;the levels of A.muciniphila in feces; | — |
Secondary
| Measure | Time frame |
|---|---|
| Crohn's Disease Activity Index;ulcerative colitis Myao score; | — |
Countries
China
Contacts
Public ContactHu Zhang
West China Hospital of Sichuan University
Outcome results
None listed