Hyperuricemia
Conditions
Interventions
Diglyceride oil intervention group:Replace the oil from the stir-fry with the product provided - 80% diglyceride cooking oil
Sponsors
Shanghai Jiao Tong University School of Medicine
Eligibility
Sex/Gender
All
Age
25 Years to 50 Years
Inclusion criteria
Inclusion criteria: (1) 25 years old= age = 50 years old, male-to-female ratio: 2:1, BMI>18kg/m² (excluding thin people); (2) meet the diagnostic criteria for asymptomatic hyperuricemia; Asymptomatic hyperuricemia refers to patients with only hyperuricemia (blood uric acid = 450-540 µmol/L), or (blood uric acid = 450-480 µmol/L) combined with hypertension, dyslipidemia, diabetes, obesity, stroke, coronary heart disease, cardiac insufficiency, uric acid nephrolithiasis, renal impairment (= CKD2 stage), etc., but no clinical symptoms such as arthritis, tophi, uric acid stones, etc. (3) Good diet, no daily smoking (passive or active smoking no more than 1 hour a day), no alcohol (less than 14 times a week), no heavy dieting; (4) Ensure that other drugs that affect metabolism are not consumed during this experiment. Eat at home at least 5 times a week, and consume 25g of cooking oil per day; (5) Be able to comply with the requirements of clinical trials; (6) The subject or guardian has signed the informed consent form; (7) The patient fills in the written informed consent form and the food frequency questionnaire and undertakes to cooperate with the study throughout the trial period.
Exclusion criteria
Exclusion criteria: Those who have the following conditions will not be selected: (1) No long-term use of drugs related to lipid metabolism in the past 6 months; (2) Abuse of narcotics, psychotropic substances and cigarettes in the past 6 months; (3) Supplement nutrients, such as probiotics, multi-minerals, multivitamins, etc., at least twice a week during the study period or in the past 2 months; (4) rapid weight loss in the past 6 months, total parenteral nutrition and protein malnutrition; (5) Pregnant or lactating women, or those who plan to become pregnant in the next 6 months; (6) poor compliance and poor follow-up possibility;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum uric acid; | — |
Secondary
| Measure | Time frame |
|---|---|
| height;weight;waistline; blood routine examination;Blood pressure;Fasting blood glucose;Insulin levels;Glycosylated hemoglobin;Triglycerides;Total cholesterol;HDL cholesterol;LDL cholesterol;Serum HDL;Serum low-density lipoprotein;C-reactive protein;Serum creatinine; | — |
Countries
China
Contacts
Public ContactYuanyuan Yan
Shanghai Jiao Tong University School of Medicine
Outcome results
None listed