Cirrhotic portal hypertension with gastrointestinal bleeding
Conditions
Interventions
Thrombus group :None
Control group (No thrombosis):None
Sponsors
The Second Hospital of Lanzhou University
Eligibility
Sex/Gender
All
Age
16 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) Patients with EGVB secondary to cirrhotic portal hypertension have a Child-Pugh score of A or B for liver function; (2) previous history of EGVB, and after conservative treatment (including treatment such as vascular interventional embolization, endoscopic variceal ligation and injection sclerotherapy, compression hemostasis treatment of three - cavity two - capsule tube and medication), there is still a history of gastrointestinal bleeding; (3) preoperative abdominal CT or ultrasound examination of the portal vein and its branches showed no thrombosis; (4)no liver cancer or other malignant tumors found; (5) No history of using anticoagulants before surgery; (6) adult patients who agreed to and underwent splenectomy and oesophagogastric devascularization and signed an informed consent form; (7) After evaluation, organs such as the heart, lungs, and kidneys are able to tolerate surgery and there are no obvious surgical contraindications.
Exclusion criteria
Exclusion criteria: (1) Severe dysfunction of important organs such as the heart, lungs, and kidneys that cannot tolerate surgery; (2) Individuals with severe coagulation disorders; (3) Patients with malignant tumors or other hematological diseases; (4) Accompanied by severe infections; (5) Patients with gastrointestinal bleeding without cirrhosis; (6) Patients who are unable to complete the experiment or have difficulty following medical advice.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Portal vein thrombosis, blood flow velocity; | — |
Secondary
| Measure | Time frame |
|---|---|
| Liver function, operation time, blood loss, length of hospital stay, etc.; | — |
Countries
China
Contacts
Public ContactXiaohu Guo
The Second Hospital of Lanzhou University
Outcome results
None listed