postoperative cognitive dysfunction
Conditions
Interventions
Experimental group:0.2mg/kg dilute 5ml anesthesia induction when intravenous injection
Control group:5ml physiological saline anesthesia induction of intravenous injection
Sponsors
Shanghai Sixth People's Hospital
Eligibility
Sex/Gender
All
Age
60 Years to 90 Years
Inclusion criteria
Inclusion criteria: Patients receiving hip replacement in Shanghai Sixth People's Hospital ? Age> 60 years old; ? Anesthesiology grades III Class II II; ? Unilateral hip replacement surgery; ? The Body Quality Index (BMI) is 18 ~ 30kg / m2; ? The function of the heart, liver, and kidney and lungs is basically normal; no anemia; ? Perfect case information.
Exclusion criteria
Exclusion criteria: ? Those with severe anemia; ? Those with severe hypertension and cardiovascular and cerebrovascular diseases; ? Those with central nervous system diseases, mental abnormalities, or psychological disorders pre -surgery; ? Those with cardiovascular disease or mental illness; ? People with quality and sexual dysfunctional dysfunction; ? Audiovisual disabilities and cannot communicate normally; ? Merceable secondary factor that affects the metabolism of the body, such as thyroid function hyperthyroidism
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mini-Mentai State Examination;IL-6;Calcium calcium;Postoperative pain score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood pressure;Heart rate;Arterial blood gas analysis;Feel sick and vomit; | — |
Countries
China
Contacts
Public Contactzhang nannan
Shanghai Sixth People's Hospital
Outcome results
None listed