Postoperative delirium
Conditions
Interventions
Sponsors
The First Affiliated Hospital of Soochow University
Eligibility
Sex/Gender
All
Age
60 Years to No maximum
Inclusion criteria
Inclusion criteria: 1) Age = 60 years old, male or female; 2) American classification of anesthesiologists (ASA) grades I-III; 3) Undergoing major non-cardiac surgery, with an estimated surgical time = 1.5 hours; 4) Estimated postoperative hospital stay = 2 days; 5) Having a clear understanding of the study, voluntarily participating, and providing a written informed consent.
Exclusion criteria
Exclusion criteria: 1) Emergency operation; 2) Sick sinus syndrome, heart rate (HR) <50 beats/min, second-degree or greater atrioventricular block without a pacemaker, cardiac insufficiency, liver or renal dysfunction; 3) Preoperative cognitive dysfunction (assessed by MMSE); 4) Schizophrenia, epilepsy, Parkinson's disease, preoperative use of sedative or hypnotic drugs; 5) Inability to communicate effectively or refusal to participate in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of POD; | — |
Secondary
| Measure | Time frame |
|---|---|
| Days with POD;Pain scores at rest;Pain scores on movement;Postoperative fentanyl consumption;Incidence of hypotension;Incidence of bradycardia;Incidence of PONV;Non-delirium complications;Postoperative days of hospital stay;Postoperative cognitive function;Mortality; | — |
Countries
China
Contacts
Public ContactPeng Ke
Department of Anesthesiology, The First Affiliated Hospital of Soochow University
Outcome results
None listed