Functional dyspepsia
Conditions
Interventions
The intervention group:Aurantii Fructus Immaturus Flavonoid Tablets + placebo of Domperidone
The control group:Domperidone + placebo of Aurantii Fructus Immaturus Flavonoid Tablets
Sponsors
Jiangsu Provincial People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1) Age= 18 years old, = 65 years old, gender is not limited; 2)Volunteer to participate and sign an informed consent form; 3) Meet the diagnostic criteria for functional dyspepsia; 4) Other gastric prokinetic drugs, gastric mucosal protectors, or antacids have been discontinued 4 weeks prior to enrollment.
Exclusion criteria
Exclusion criteria: 1) Patients with esophagitis, atrophic gastritis, gastric and duodenal ulcers, erosions, hemorrhages, tumors and other organic lesions; 2) Patients with hepatobiliary and pancreatic organic diseases; 3) Diabetes, kidney disease, connective tissue disease, mental illness; 4) Patients with serious primary diseases such as heart, brain, lung, kidney, hematopoietic system, endocrine system, etc.; 5) Those with a history of abdominal surgery; 6) Patients with renal insufficiency, Cr higher than the upper limit of normal; 7) Patients with hepatic insufficiency, AST or/and ALT at 1.5 times the upper limit of normal; 8) Pregnant or expecting to become pregnant, lactating women; 9) Mentally or legally disabled patients; 10) Those who participated in other drug clinical trials within 3 months before the trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The disappearance rate of all four symptoms of functional dyspepsia; | — |
Secondary
| Measure | Time frame |
|---|---|
| The disappearance rate of all four symptoms of functional dyspepsia;The disappearance rate of single symptoms of functional dyspepsia ; Gastric emptying rate and emptying time; | — |
Countries
China
Contacts
Public ContactMuxin Wei
Jiangsu Provincial People's Hospital
Outcome results
None listed