Chronic Heart Failure
Conditions
Interventions
Experimental Group:Standardized Western medicine treatment combined with Optimized New Shengmai Powder
Sponsors
First Teaching Hospital of Tianjin University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
35 Years to 79 Years
Inclusion criteria
Inclusion criteria: (1) Age from 35 to 79 (including boundary value), gender not limited; (2) Diagnosed as chronic heart failure according to the western medicine criteria; (3) Grade II to III (NYHA cardiac functional classification); (4) Complying with the TCM syndrome differentiation standard of qi deficiency, blood stasis with water retention; (5) No Chinese medicine taken within 2 weeks; (6) Informed consent signed.
Exclusion criteria
Exclusion criteria: (1) Acute heart failure; (2) Those who have one of the following diseases: Acute coronary syndrome within 30 days; revascularization therapy within 6 months; uncontrolled hypertension with systolic pressure more than or equal to 180mmHg and/or diastolic pressure more than or equal to 110mmHg; second-degree type 2 or worse sinoatrial /atrioventricular block without implantation of a pacemaker or uncontrolled malignant cardiac arrhythmia; hypertrophic obstructive cardiomyopathy; myocarditis; pulmonary artery embolism; severe valvular heart disease; pulmonary heart disease; stroke within 6 months; (3) Individuals who are unable to undergo cardiopulmonary exercise tests due to physical disabilities or other reasons; (4) Individuals with severe endocrine disorders such as hyperthyroidism, severe anemia (hemoglobin = 9g/dl), or other diseases that affect survival (such as malignant tumors); (5) Patients with abnormal liver and kidney function (Alanine aminotransferase (ALT) and/or serum creatinine > 2 times the upper limit of normal); (6) Suspicious or definite allergy to intervention drugs; (7) Participated in other trials within 2 months; (8) Being pregnant, planning for pregnancy or breastfeeding; (9) Evaluated to be unsuitable to participate in the study by the researcher.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 6-minute walking distance;Peak oxygen consumption; | — |
Secondary
| Measure | Time frame |
|---|---|
| MLHFQ score;MLHFQ in the principle of Chinese civilization and traditional medicine characteristics score;Information scoring of four diagnostic methods in TCM;New York Heart Association (NYHA) cardiac functional classification;Echocardiography indexes;BNP; | — |
Countries
China
Contacts
Public ContactXianliang Wang
First Teaching Hospital of Tianjin University of Traditional Chinese Medicine
Outcome results
None listed