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A Study on the correlation of Flash Electroretinogram Indexes and Negative Symptoms of Schizophrenia

A Study on the correlation of Flash Electroretinogram Indexes and Negative Symptoms of Schizophrenia

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400083043
Enrollment
Unknown
Registered
2024-04-15
Start date
2024-04-15
Completion date
Unknown
Last updated
2024-04-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Schizophrenia

Interventions

Schizophrenia Patient:N/A

Sponsors

Shanghai Mental Health Center
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Disease group: Diagnosed with schizophrenia according to ICD-10 criteria, no other severe mental disorder diagnosis, aged 18-60 years old, currently hospitalized in Shanghai Mental Health Center, have signed informed consent form; Control group: Shanghai mental health center employees who have no diagnosis of severe mental disorders and are matched in age, gender, and disease group, have signed informed consent forms;

Exclusion criteria

Exclusion criteria: Exclusion criteria: 1. Ophthalmic diseases such as glaucoma, retinopathy, high myopia, cataracts, etc. that cause errors in the measurement of retinal electrophysiology or flash retina; 2. Intellectual developmental disorders; 3. Diseases that cause neuroretinal atrophy, including brain trauma, neurological disorders, poorly controlled cardiovascular and metabolic diseases (average blood pressure>135/85mmHg, glycated Hb>6.5, fasting TG>1.7mmol/L, HDL-C<1.04mmol/L); 4. History of disorders in the use of psychoactive substances; 5. Unable to cooperate; 6. Have a history of electroconvulsive therapy in the past six months; 7. Optical coherence tomography examination revealed abnormal retinal structure.

Design outcomes

Primary

MeasureTime frame
photoptic b-wave;SANS scale;

Countries

China

Contacts

Public ContactZhu Jiayi

Shanghai Mental Health Center

2696275866@qq.com+86 189 1324 5940

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026