Amyloidosis
Conditions
Interventions
Gold Standard:Genetic testing or tissue biopsy
(If not available, comprehensive clinical symptoms, laboratory tests, and imaging examination results will be taken.)
Index test:18F-Florbetapir imaging,99mTc-PYP imaging
Sponsors
The First Affiliated Hospital of Chongqing Medical University
Eligibility
Sex/Gender
All
Age
No minimum to 100 Years
Inclusion criteria
Inclusion criteria: 1. Patients with clinical diagnosis of any type of systemic amyloidosis 2. Evidence of cardiac amyloidosis, if cardiac involvement, is defined as any (or more) of the following: A. cardiac involvement (including cardiac biomarkers) as defined by international consensus criteria for amyloidosis B. cardiac involvement in MRI imaging of the heart 3. Informed consent.
Exclusion criteria
Exclusion criteria: 1. Unable to lie flat 2. NYHA grade IV heart failure 3. Pregnancy or breastfeeding 4. Known allergy to radioactive injections
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 18F-Florbetapir imaging organ uptake status;99mTc-PYP imaging organ uptake status; | — |
Countries
China
Contacts
Public ContactPang Hua
The First Affiliated Hospital of Chongqing Medical University
Outcome results
None listed