Shallow corneal defects caused by various reasons
Conditions
Interventions
Trial group:Using the experimental group's biological amniotic membrane
Control group:Using control group biological amniotic membrane
Sponsors
Beijing Tongren Hospital, CMU
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: (1) Patients with superficial corneal defects caused by various reasons; (2) Age = 18 years old, regardless of gender; (3) Voluntarily participate in this experiment and sign an informed consent form.
Exclusion criteria
Exclusion criteria: (1) The depth of corneal defect is greater than one-third of the thickness of the corneal layer; (2) Chemical or thermal burns with corneal limbal ischemia exceeding one-third; (3) Eye infections are in the active phase; (4) Glaucoma patients; (5) Patients with diabetes complicated with retinal detachment and other fundus diseases are not suitable for the group according to the judgment of the researcher; (6) Eyelid defects, incomplete closure of the eyelids, entropion of the eyelids, ectropion of the eyelids, and other eyelid abnormalities determined by the researcher as unsuitable for inclusion; (7) Severe allergic constitution or allergy to test materials and medication; (8) Pregnant, planned or breastfeeding women; (9) Individuals who have participated in clinical trials of other medical devices within one month, or have participated in drug clinical trials within three months; (10) Other situations that the researcher deems unsuitable for participation in this experiment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Effective rate of repairing superficial corneal defects 28 days after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| Corneal defect area;Amniotic membrane occupancy rate;Conjunctival congestion rating;Eye irritation symptoms; | — |
Countries
China
Contacts
Public ContactYing Jie
Beijing Tongren Hospital, CMU
Outcome results
None listed