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Clinical pregnancy rate of patients with mild intrauterine adhesions treated with PRP perfusion immediately after hysteroscopy: a prospective, single arm, multicenter clinical study

Clinical pregnancy rate of patients with mild intrauterine adhesions treated with PRP perfusion immediately after hysteroscopy: a prospective, single arm, multicenter clinical study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400082997
Enrollment
Unknown
Registered
2024-04-12
Start date
2024-05-01
Completion date
Unknown
Last updated
2024-04-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intrauterine adhesions

Interventions

PRP intrauterine perfusion:Immediately perform PRP intrauterine perfusion after hysteroscopy

Sponsors

Zhongshan Hospital Fudan University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 40 Years

Inclusion criteria

Inclusion criteria: 1) Volunteer to join this research project; 2) Age 20-40 years old; 3) Ultrasound diagnosis of endometrial adhesions requires hysteroscopic separation surgery, and the IUA score is less than 8 points; Basic FSHB3bb;

Exclusion criteria

Exclusion criteria: 1) Individuals with chromosomal abnormalities in both spouses; 2) Individuals with blood system diseases and abnormal coagulation function; 3) Patients with combined uterine developmental abnormalities (bicornuate uterus, single uterus, etc.), fallopian tube effusion, and pelvic tuberculosis; 4) Patients with concurrent endocrine diseases and gonadal dysgenesis; 5) History of severe liver and kidney, cardiovascular and cerebrovascular diseases, and hematological malignancies; 6) Hereditary ovarian insufficiency; 7) Previous major lower abdominal surgery resulting in pelvic adhesions; 8) Contraindications to the use of anticoagulants during plasma infusion and current or past IgA deficiency; 9) Acute and chronic infection period of the uterine cavity and vagina;

Design outcomes

Primary

MeasureTime frame
clinical pregnancy rate;

Secondary

MeasureTime frame
Biochemical pregnancy rate;Miscarriage rate;Uterine intrauterine adhesion score;

Countries

China

Contacts

Public ContactWang jing/Dong xi

Zhongshan Hospital Fudan University

wang.jing4@zs-hospital.sh.cn+86 188 1696 8983

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026