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The effect of electrotherapy on cognitive symptoms of depression and the exploration of neural mechanisms based on near-infrared functional brain imaging (fNIRS)

The effect of electrotherapy on cognitive symptoms of depression and the exploration of neural mechanisms based on near-infrared functional brain imaging (fNIRS)

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400082987
Enrollment
Unknown
Registered
2024-04-12
Start date
2024-05-15
Completion date
Unknown
Last updated
2024-04-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

depression

Interventions

Experiment 1: Experimental group:Electroacupuncture Baihui, Yintang, Sishencong, 15 minutes each time.
Experiment 1:Control group:Oral paroxetine hydrochloride tablets, 20mg, once a day.
Experiment 2:The patients were divided into 5 types of syndrome, such as liver-qi stagnation syndrome, phlegm-heat disturbance syndrome, heart-spleen deficiency syndrome, heart-kidney Yin deficiency s

Sponsors

Shaanxi Provincial Hospital of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: (1) Meet the DSM-5 diagnostic criteria for depression. (2) Self-assessment of cognitive Impairment Questionnaire (PDQ-D) =21 scores. (3) For the first time and have not received acupuncture treatment and western antidepressant treatment in the past, or have not received Western drugs in the last 2 months Drugs for antidepressant treatment of depressed patients. (4) 8 =17 Hamilton Depression Scale (HAMD) =24 points. (5) Age 18-60. (6) Informed and signed consent to participate in the researcher.

Exclusion criteria

Exclusion criteria: (1) Depression caused by other serious mental illnesses, such as schizophrenia, bipolar disorder, obsessive-compulsive disorder, etc. (2) Serious risk and behavior of suicide and self-injury. (Hamilton Depression Scale (HAMD--17) 3 Item =2 marks) (3) Pregnant and nursing women. (4) Patients who had received neuroregulatory techniques such as electroshock, transcranial magnetism, and transcranial direct current within 6 months before admission. (5) Patients with previous dizziness. (6) There is skin damage at the acupuncture site.

Design outcomes

Primary

MeasureTime frame
PDQ-D;

Secondary

MeasureTime frame
HAMD-17;

Countries

China

Contacts

Public ContactLei Yaling

Shaanxi Provincial Hospital of Traditional Chinese Medicine

Leiyaling520@163.com+86 130 3298 7128

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026