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Neoadjuvant Chemotherapy combined with Bevacizumab for resectable Colorectal Liver Metastasis with High Recurrence Risk Factors

Neoadjuvant Chemotherapy combined with Bevacizumab for resectable Colorectal Liver Metastasis with High Recurrence Risk Factors

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400082966
Enrollment
Unknown
Registered
2024-04-11
Start date
2024-04-12
Completion date
Unknown
Last updated
2024-04-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colorectal cancer liver metastasis

Interventions

Group of Neoadjuvant Chemotherapy:None
Group of Neoadjuvant Chemotherapy combined with Bevacizumab:None

Sponsors

Fujian Provincial Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: (1) The primary tumor was histologically confirmed as colorectal adenocarcinoma, which was resectable or resected; (2) aged 18 years or above; (3) The liver mass was confirmed as colorectal cancer metastasis by conventional pathology; (4) Liver metastases were evaluated as resectable status before neoadjuvant chemotherapy; (5) Patients had not received any local treatment before neoadjuvant therapy, including radiotherapy, interventional therapy, etc. (6) Patients with CRS score > 2 points and good function of important organs.

Exclusion criteria

Exclusion criteria: (1) subjects who used anticoagulants, hormones, immunosuppressants, or drugs of abuse before surgery (which may interfere with the test results); (2) patients with a history of malignant tumors other than colorectal cancer; (3) Distant metastasis outside the liver was found by preoperative imaging or during operation; (4) missing important clinical data, including lost follow-up; (5) any diseases that may interfere with the test results after evaluation.

Design outcomes

Primary

MeasureTime frame
patient information;

Countries

China

Contacts

Public ContactLi Weihua

Fujian Provincial Hospital

175690701@qq.com+86 135 7535 3271

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026