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Efficacy and safety of ultrasound-guided superior laryngeal nerve block in the prevention of postoperative sore throat after radical thyroidectomy: A prospective randomized controlled double-blind study

Efficacy and safety of ultrasound-guided superior laryngeal nerve block in the prevention of postoperative sore throat after radical thyroidectomy: A prospective randomized controlled double-blind study

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400082959
Enrollment
Unknown
Registered
2024-04-11
Start date
2024-05-01
Completion date
Unknown
Last updated
2025-03-31

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative sore throat

Interventions

Study group and observation group:Superior laryngeal nerve block
Observation group:None

Sponsors

The Second Affiliated Hospital of PLA Army Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Patients who met the surgical indications of radical thyroid cancer and planned to undergo thyroidectomy, unilateral thyroidectomy, total thyroidectomy, or the above surgical methods combined with central lymph node dissection; 2. American Society of Anesthesiologists (ASA) I- II; 3. Aged from 18 to 65.

Exclusion criteria

Exclusion criteria: 1. Patient refused to participate in the study; 2. Difficult airway or suspected difficult airway (Mallampati grade III-IV); 3 .Preoperative sore throat, chronic pharyngitis and reflux esophagitis; 4. Preoperative hoarseness; 5. Patients who required continuous use of anticoagulants or antiplatelet drugs or inhaled corticosteroids or antihypertensive drugs before surgery; 6. High risk of reflux or aspiration; 7. Patients with dysphagia; 8. Smokers, alcoholics, and illicit drug users; 9. Infection at the puncture site; 10. Patients with allergy to local anesthetics; 11. Patients with previous oral or throat surgery history; 12. Upper respiratory tract infection within 2 weeks before surgery; 13. The expected operation time was more than 4 hours; 14. BMI > 30 kg/ m2; 15. Patients with severe cognitive impairment or other disorders that may cause dysphonia; 16. Patients participating in other clinical research projects.

Design outcomes

Primary

MeasureTime frame
Sore throat score ;

Secondary

MeasureTime frame
Incidence of sore throat, choking cough, dysphonia and hoarseness ;Incidence of choking cough,vocal disorder and hoarseness ;Incidence of sore throat, choking cough,vocal disorder and hoarseness ;Incidence of choking cough,vocal disorder and hoarseness ;Mucosal injury grading;

Countries

China

Contacts

Public ContactDingJinping

The Second Affiliated Hospital of PLA Army Medical University

dingjp240223@tmmu.edu.cn+86 180 8301 0733

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026