Painless gastroscopy patients
Conditions
Interventions
A group:Anesthesia induction was performed using Remazolam and Alfentanil at a dose of 5ug/kg, with Remazolam administered for 10 seconds. Using a biased coin design up and down sequential method (BCD
P group:Anesthesia induction was performed using Remazolam and Alfentanil at a dose of 5ug/kg, with Remazolam administered for 10 seconds. Using a biased coin design up and down sequential method (BCD
Sponsors
The First Affiliated Hospital of Zhengzhou University
Eligibility
Sex/Gender
All
Age
18 Years to 59 Years
Inclusion criteria
Inclusion criteria: 1) Painless gastroscopy under intravenous anesthesia 2) ASA classification I-II 3) Aged 18-60 years old 4) Voluntarily participate in this study and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1) Allergy to benzodiazepines and opioids 2) Sleep disorders 3) Long-term history of taking sedative and analgesic drugs 4) Pathological obesity/obstructive sleep apnea 5) Acute upper respiratory tract infection 6) Asthma attack period 7) Uncontrolled severe hypertension 8) Unstable angina 9) Severe liver dysfunction 10) Acute upper gastrointestinal bleeding accompanied by shock 11) Severe anemia 12) Gastrointestinal obstruction accompanied by gastric content retention 13) Schizophrenia and severe depression.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Depth of anesthesia;Sleep quality; | — |
Secondary
| Measure | Time frame |
|---|---|
| Remimazolam dosage;Alfentanil dosage;Alert time; | — |
Countries
China
Contacts
Public ContactDan Cheng
The First Affiliated Hospital of Zhengzhou University
Outcome results
None listed