Autologous Blood Transfusion Undergoing Spinal Surgery
Conditions
Interventions
Group A (dose of transfusion of shed autologous blood =600mL):NA
Group B (600mL1200mL):NA
Sponsors
Suzhou Hospital Affiliated to Nanjing Medical University
Eligibility
Sex/Gender
All
Age
40 Years to 75 Years
Inclusion criteria
Inclusion criteria: a) Aged between 50 and 75 years; and with ASA grade of I–II. b) Uncontaminated blood during autologous transfusion c) Willing to receive autologous or allogeneic blood transfusion d) All patients underwent surgery for the first time and were scheduled for elective surgery. e) Preoperative hemoglobin > 90g/L
Exclusion criteria
Exclusion criteria: a)Patients with spinal tumors, spinal tuberculosis. b)Patients with severe hypertension, diabetes, and severe cardiopulmonary insufficiency. c)Patients with liver and kidney insufficiency, chronic hepatitis and severe cirrhosis, malnutrition and hypoproteinemia. d)Patients with severe hypothermia, vitamin K deficiency, thrombocytopenia, or abnormal functioning.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| activated clotting time;IL-6; | — |
Secondary
| Measure | Time frame |
|---|---|
| activated partial thromboplastin time;prothrombin time;Platelet,PLT;TNF-a;IL-10;volume of wound drains ; | — |
Countries
China
Contacts
Public ContactYang Xie
Suzhou Hospital Affiliated to Nanjing Medical University
Outcome results
None listed