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Intra-articular injection of near-infrared activated platelet-rich plasma in the treatment of meniscus injury

Intra-articular injection of near-infrared activated platelet-rich plasma in the treatment of meniscus injury

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400082940
Enrollment
Unknown
Registered
2024-04-11
Start date
2024-04-15
Completion date
Unknown
Last updated
2024-04-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

meniscus injury

Interventions

Control group:Unactivated platelet-rich plasma intra-articular injection therapy
Photoactivated platelet-rich plasma group:PRP was injected into the knee joint cavity after near-infrared irradiation (distance 10 cm, time 10 min).

Sponsors

The General Hospital of Western Theater Command
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1.According to the diagnostic criteria of meniscus injury in ' bone and joint injury ', MRI examination of knee joint showed that the degree of meniscus injury was grade I / II or grade III injury, which was not suitable for surgical treatment ; 2.Patients aged 18-65 years, regardless of gender ; 3.Patients understand the main contents and risks of this study, voluntarily participate in and sign informed consent.

Exclusion criteria

Exclusion criteria: 1.There was a history of knee surgery in the affected joint; 2.Non-stable period of severe cardiovascular and cerebrovascular diseases, cardiac pacemaker surgery the latter; 3.Anticoagulant allergy, coagulation and hematopoietic dysfunction, sepsis; 4.Combined with liver and kidney failure, suffering from malignant tumors; 5.Any reason can not cooperate with any other situation of the study;

Design outcomes

Primary

MeasureTime frame
MRI examination results: meniscus injury grading;Knee Injury and Osteoarthritis Outcome Score (KOOS);

Secondary

MeasureTime frame
the International Knee Documentation Committee (IKDC) score;Inflammatory factors;VAS, visual analog scale;rate of knee joint surgery within three months after treatment;

Countries

China

Contacts

Public ContactWei Wu

The General Hospital of Western Theater Command

1255379844@qq.com+86 130 0810 7300

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026