Sepsis
Conditions
Interventions
intervention group with Berberine:Berberine and compound vitamin B tablets were crushed into powder, dissolved in water, and fed nasally with a 50ml syringe 3 times a day for 7 days or patients were t
Control group:Compound vitamin B (similar in appearance to berberine) 2 tablets, administration route and method were consistent with the treatment group
Sponsors
General Hospital of Southern Theatre Command
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Hospitalized patients with sepsis and acute gastrointestinal injury, older than 18 years and younger than 80 years.
Exclusion criteria
Exclusion criteria: Acute central nervous system diseases (stroke, traumatic brain injury); Severe abdominal trauma; Acute myocardial infarction, severe arrhythmia, heart failure and shock (IABP), cardiopulmonary resuscitation; Primary neuromuscular disease; Drug, alcohol, opioid or amphetamine-type drug dependence, mental disorders; Pregnant women; Advanced malignant tumor or dysphoria, end-stage chronic disease; Patients expected to die within 24 hours in ICU; Past berberine allergy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Classification of acute gastrointestinal injury;D-lactic acid; | — |
Secondary
| Measure | Time frame |
|---|---|
| lipolyaccharide; | — |
Countries
China
Contacts
Public ContactLiu zhifeng
General Hospital of Southern Theatre Command
Outcome results
None listed