Thoracic diseases
Conditions
Interventions
Ciprofol group:Anesthesia induction at 0.4 mg/kg, anesthesia maintained at an initial pump rate of 0.8 mg/kg/h, with each fluctuation of 0.1-0.4 mg/kg/h, and overall control at 0.8-2.4 mg/kg/h
Propofol gruop:Anesthesia induction 2.0 mg/kg, anesthesia maintained at an initial pump speed of 6mg/kg/h, with each fluctuation of 1-2 mg/kg/h, and overall control at 4-12 mg/kg/h
Sponsors
Fuyang Normal University Second Affiliated Hospital (Fuyang Fifth People’ s Hospital)
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) Age 18-75; (2) ASA class II-III; (3) Body mass index (BMI) 18.5-27.9kg/m2; (4) Patients scheduled for thoracoscopic surgery; (5) No history of relevant drug allergies.
Exclusion criteria
Exclusion criteria: (1) History of mental and neurological disorders (such as cerebrovascular disease, epilepsy, senile dementia, schizophrenia, and depression) (2) Patients with multiple chronic diseases who cannot tolerate surgical anesthesia (3) Severe heart, lung, and kidney dysfunction (4) Recently, there has been a history of using drugs such as cyclophosphamide and propofol (5) Individuals with a history of drug allergies and contraindications (6) Patients with alcohol or drug abuse within 3 months
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Fluid replacement volume;Blood loss volume;Urine volume;Number of times vasoactive drugs are used during surgery; | — |
Primary
| Measure | Time frame |
|---|---|
| Modified observer's assessment of alert / sedation;Bispectral index;Changes in blood pressure during surgery;Pulse oximetry;Heart rate;Wake-up time;Reatment emergent adverse events;Number of successful and failed anesthesia induction attempts;Number of successful and failed attempts in maintaining anesthesia;Number of drug additions during induction phase; | — |
Countries
China
Contacts
Public ContactYaodong Yan
Fuyang Normal University Second Affiliated Hospital (Fuyang Fifth People’ s Hospital)
Outcome results
None listed