Sudden sensorineural hearing loss
Conditions
Interventions
Experiment Group 1 (Experiment Group):Acupuncture combined with intratympanic injection of dexamethasone
Experiment Group 2 (Control Group):Sham acupuncture combined with intratympanic injection of dexamethasone
Sponsors
Eye and ENT Hospital of Fudan University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Patients regardless of gender, aged 18-65 years (inclusive); 2. Unilateral hearing loss patients diagnosed with sudden sensorineural hearing loss in accordance with the American Association of Otolaryngology Head and Neck Surgeons (AAO-HNS) diagnosis and treatment guidelines, with idiopathic hearing loss (diagnostic criteria: sensorineural hearing loss that occurs suddenly within 72 hours and of unknown cause, with a hearing loss of = 30dB in at least three adjacent frequencies of 0.5KHz/1KHz/2KHz/4KHz) (on the day of enrollment); 3. Patients within 14 days of onset; 4. The patient has unilateral onset of the disease and has a history of symmetrical hearing in both ears.
Exclusion criteria
Exclusion criteria: 1. Patients with a history of hearing abnormalities in the affected ear or the opposite ear; 2. Patients with concomitant diseases of the inner ear, such as Meniere's disease, vestibular neuritis, labyrinthitis, otosclerosis, benign paroxysmal positional vertigo, vestibular aqueduct enlargement, Mondini malformation, inner ear tumors, etc; 3. Patients with contraindications to intratympanic glucocorticoid injection; 4. Patients who have received glucocorticoid therapy within 14 days of onset; 5. Women who are breastfeeding, pregnant, or potentially pregnant; 6. Patients with severe cervical spondylosis, fractures, mental disorders, and other illnesses; 7. Patients who are unable to cooperate with medication and examinations; 8. Patients who are allergic to the prescribed medication in the plan; 9. Patients who have participated in clinical trials of other drugs or devices within the past three months; 10. Patients with skin lesions, scars, etc. at acupoints that affect acupuncture treatment; 11. Other situations deemed unsuitable for this experiment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pure tone threshold; | — |
Secondary
| Measure | Time frame |
|---|---|
| Word Recognition Score;Tinnitus Handicap Inventory;Quality of Life;Hospital anxiety and depression scale; | — |
Countries
China
Contacts
Public ContactRen Dongdong
Eye and ENT Hospital of Fudan University
Outcome results
None listed