Achalasia
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Achalasia group: 1. Age 18-80 years old, male or female; 2. Achalasia of cardia was confirmed by upper gastrointestinal angiography or esophageal manometry, and POEM was performed in our hospital; 3 Sign the informed consent form. Control group: 1. Age 18-80 years old, male or female; 2. Healthy people undergoing endoscopy; 3 Sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. A history of upper gastrointestinal surgery, ulcers and tumors; 2. There are serious concomitant diseases that affect the evaluation of this study, such as heart disease, lung disease, liver disease, kidney disease, metabolic disease, mental disease, and malignant tumor; 3. Pregnant or lactating women, patients with a family plan during the study period; 4. Patients who have taken antibiotics and immunosuppressants in the past 3 months; 5. Take PPIs for the last 2 weeks; 6. Refusing to participate in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Microbial spectrum; | — |
Secondary
| Measure | Time frame |
|---|---|
| adverse event incidence rate; | — |
Countries
China
Contacts
The First Affiliated Hospital of Nanjing Medical University