Epilepsy
Conditions
Interventions
Case series:None
Sponsors
The Second Affiliated Hospital of the Army Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1) Patients diagnosed with drug-resistant epilepsy requiring the implantation of deep brain electrodes for treatment; 2) At least one electrode contact of the implanted deep electrodes passes through the claustrum and successfully implements functional electrical stimulation; 3) Wechsler Intelligence Scale, memory score >60; 4) Possess normal communication skills; 5) Aged 18 to under 60 years old.
Exclusion criteria
Exclusion criteria: 1) Presence of significant malformations or abnormalities in brain structure; 2) Previous history of craniotomy or intracranial electrode implantation surgery; 3) Strong adverse reactions to functional electrical stimulation, such as palpitations, fear, and epileptic seizures; 4) Presence of other comorbidities, already having or requiring the implantation of cardiac pacemakers, defibrillators, and cochlear implants, etc.; 5) Presence of tumors, severe abnormalities in liver or kidney function (indicators exceeding normal values by threefold), and other serious health-affecting comorbid diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Electroencephalographic changes; | — |
Secondary
| Measure | Time frame |
|---|---|
| Electrical stimulation of behavioral symptoms; | — |
Countries
China
Contacts
Public ContactZhang Chunqing
The Second Affiliated Hospital of the Army Medical University
Outcome results
None listed