Postoperative delirium
Conditions
Interventions
Oliceridine group:Using Oliceridine for postoperative patient-controlled analgesia in patients.
Morphine group:Using morphine for postoperative patient-controlled analgesia in patients.
Sponsors
Qingdao Municipal Hospital
Eligibility
Sex/Gender
All
Age
65 Years to 90 Years
Inclusion criteria
Inclusion criteria: Patients selected to undergo general anesthesia non cardiac surgery in our hospital, aged 65-90 years old, weighing 50-90kg, ASA I-III grade, with a surgery time of 2-5 hours.
Exclusion criteria
Exclusion criteria: 1. Preoperative Mini Mental State Scale (MMSE) score = 23 points; 2. History of severe mental or neurological disorders; 3. History of drug or psychotropic substance abuse; 4. Preoperative concomitant type III or IV hepatic encephalopathy; 5. Severe visual and hearing impairment; 6. Allergies to Oxalidine or Morphine 7 Preoperative lung function examination shows moderate or severe ventilation dysfunction.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative delirium; | — |
Secondary
| Measure | Time frame |
|---|---|
| Intraoperative vital signs (ABP, HR, oxygen saturation, etc.);blood transfusion;Intraoperative urine;Number of patients without opioids and consumption of opioid drugs (morphine) and adverse reactions within 24 hours after surgery Number of patients without opioids and consumption of opioid drugs (morphine) and adverse reactions within 24 hours after surgery;Postoperative stay time in the recovery room and the number of ICU cases and stay time; | — |
Countries
China
Contacts
Public ContactYanlin Bi
Qingdao Municipal Hospital
Outcome results
None listed