obstructive left sided colon cancer
Conditions
Interventions
Simple colostomy group:NA
Emergency operation group:NA
SEMS implantation group:NA
Sponsors
West China Hospital of Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: To be eligible for the trial, patients had to meet all of the following eligibility criteria: ?. Patients voluntarily participated in this study and signed informed consent. ?. Age: 18-75 years old; ?. Colonoscopy and biopsy were performed, and adenocarcinoma was confirmed by pathology; ?. Clinical manifestations and imaging examination confirmed that the patient had locally advanced colorectal cancer (left colon cancer) with complete colonic obstruction from the distal splenic flexure of colon to 10cm from the anus; ?. Preoperative chest and abdominal CT examination was performed to confirm the tumor stage, assess the tumor resectable, and exclude distant metastasis ?. Patients who were assessed as needing and able to tolerate endoscopic treatment and surgical relief of obstruction (mainly based on the patient's ASA classification and whether they could independently complete the biochemical quality assessment questionnaire); ?. There was no other history of cancer.
Exclusion criteria
Exclusion criteria: Exclusion criteria: Patients with one of the following conditions could not be included in this study: ?. Patients with colon cancer proximal to the splenic flexure and rectal cancer less than 10 cm from the anal margin; ?. Multiple primary colorectal cancer; ?. Patients whose tumors cannot be removed or whose palliative care is planned; ?. Confirmed or suspected tumor metastasis and the presence of tumors in other organs; ?. Patients whose ECOG score is greater than 2 points or KPS score =70 points, whose physical condition cannot tolerate chemotherapy or surgery; ?. The patient has signs of peritonitis or intestinal perforation; ?. Patients who did not undergo endoscopic or surgical treatment; ?. Pathological diagnosis of non-adenocarcinoma, such as lymphoma, squamous cell carcinoma; ?. Patients with severe active infection; ? Patients who have not signed informed consent; ?. Patients in pregnancy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Complications occurred within 60 days after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| Mortality within 60 days after surgery;Tumor recurrence rate within 3 years after operation;Progression-free survival within 3 years after surgery;Overall survival rate within 3 years after operation; | — |
Countries
China
Contacts
Public ContactYang Lie
Division of Gastrointestinal Surgery, Department of General Surgery
Outcome results
None listed