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The effect of pressure driven lung protective ventilation on postoperative pulmonary complications in obese patients undergoing abdominal surgery

The effect of pressure driven lung protective ventilation on postoperative pulmonary complications in obese patients undergoing abdominal surgery

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400082865
Enrollment
Unknown
Registered
2024-04-10
Start date
2024-05-01
Completion date
Unknown
Last updated
2024-04-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative pulmonary complications

Interventions

Test group:Implementation of lung protective ventilation strategy guided by driving pressure during surgery
Control group:Implementing traditional lung protective ventilation strategy during surgery

Sponsors

Sichuan Academy of Medical Sciences · Sichuan Provincial People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: (1) 18 = Age = 80 years old (2) undergoes abdominal surgery under general anesthesia for more than 2 hours (3) BMI = 28 kg/m2 (4) ASA I-III level (5) understands the procedures and methods of this study, is willing to sign an informed consent form, and strictly adheres to the trial protocol to complete this study.

Exclusion criteria

Exclusion criteria: (1) History of pulmonary surgery; (2) History of invasive mechanical ventilation within 30 days prior to surgery; (3) History of radiotherapy and chemotherapy within 2 months prior to surgery; (4) Severe chronic obstructive pulmonary disease with preoperative pulmonary infection, pleural effusion, pneumothorax, atelectasis, thoracic drainage tube, respiratory failure; (5) Severe heart disease defined as New York Heart Association grade III or IV, acute coronary syndrome, or persistent ventricular tachycardia (6) Severe pulmonary arterial hypertension is defined as systolic pulmonary arterial pressure>40 mmHg (7) subjects who, in the opinion of the researchers, have any other unfavorable factors to participate in this trial.

Design outcomes

Primary

MeasureTime frame
Postoperative pulmonary complications;

Secondary

MeasureTime frame
Unplanned ICU occupancy rate;Hospital stay;Postoperative acute myocardial infarction;Postoperative acute kidney injury;

Countries

China

Contacts

Public ContactLei Qian

Sichuan Academy of Medical Sciences · Sichuan Provincial People's Hospital

leiqianggh@163.com+86 177 4433 9891

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026