Lumbar Instability and Lumbar Spondylolisthesis
Conditions
Interventions
Group A:Unilateral Biportal Endoscopy Transforaminal Lumbar Interbody Fusion
Group B:Minimally Invasive Transforaminal Lumbar Interbody Fusion
Sponsors
The Seventh Affiliated Hospital of Sun Yat-sen University
Eligibility
Sex/Gender
All
Age
30 Years to 80 Years
Inclusion criteria
Inclusion criteria: Patients eligible for inclusion meet the following criteria: (1) Single-segment degenerative or isthmic lumbar spondylolisthesis (Meyerding Grades I and II): vertebral slippage not exceeding one-half of the vertebral body's sagittal diameter; (2) Single-segment lumbar segmental instability: dynamic X-ray showing sagittal plane displacement of the slipped vertebra =3 mm and/or an increase in segmental sagittal motion (extension or flexion positioning resulting in an intervertebral angle =11°); (3) Presence of lower back pain and/or symptoms of radicular pain, numbness, weakness, or intermittent claudication in the lower extremities; (4) Ineffectiveness of conservative treatment for a duration of 3 months.
Exclusion criteria
Exclusion criteria: Patients with one or more of the following conditions are excluded from the study: (1) Systemic or localized active infection; (2) Malignant tumors: Patients with a confirmed history of malignancy (excluding non-malignant melanoma), unless they have undergone effective treatment and have been free of clinical symptoms and signs for at least 5 years; (3) History of lumbar spine surgery, or presence of other spinal diseases such as ankylosing spondylitis, spinal tumors, spinal fractures, or neurological diseases; (4) Coexisting significant organ pathology or other reasons that preclude the patient from undergoing or tolerating surgery, or an American Society of Anesthesiologists (ASA) classification of IV or higher; (5) Cognitive and psychological disorders and other diseases that make participation in the study inappropriate; (6) Refusal to sign the informed consent form.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Oswestry Disability Index; | — |
Secondary
| Measure | Time frame |
|---|---|
| Japanese Orthopaedic Association Scores, JOA;Quebec Back Pain Disability Scale, QBPDS;Visual Analogue Scale, VAS;Radiological measurements;Surgery related conditions;Low back muscle function evaluation; | — |
Countries
China
Contacts
Public ContactQiji Li
The Seventh Affiliated Hospital of Sun Yat-sen University
Outcome results
None listed