Type 2 Diabetes
Conditions
Interventions
Intervention group:Use instant food for daily lunch substitutions and give individualized diabetes diet education
control group:only individualized diabetes diet education
Sponsors
Peking University First Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1) Patients with type 2 diabetes who are at least 18 years of age; 2) The condition is stable, the patient has not taken medication, or has used medication and the treatment regimen (type and dose) has been stable for at least 3 months; (Permitted drugs include: metformin, sulfonylureas, thiazolidinediones, dipeptidyl peptidase-IV inhibitors, glucagon-like peptide-1 agonists); 3) body mass index (BMI)=24; 4) 6.5%=HbA1C<10%.
Exclusion criteria
Exclusion criteria: 1) Clinically diagnosed as type 1 diabetes mellitus (T1DM), specific type diabetes mellitus or gestational diabetes mellitus; 2) Clinically confirmed diagnosis of secondary hyperglycemia caused by other reasons; 3) Patients treated with insulin; 4) Other diseases that affect glucose metabolism (such as hyperthyroidism or hypercortisolism); 5) With severe diabetes related diseases (proliferative diabetic retinopathy, eGFR 1.2 times the upper limit of normal value; 11) nephrotic syndrome; 12) Severe gastrointestinal diseases or normal structural changes of the gastrointestinal tract, such as active inflammatory bowel disease, sleeve gastric surgery, Roux-en-Y gastrojejunal anastomosis, etc.; 13) Pregnant or lactating women; 14) People who may be allergic to the subject. 15) Fasting blood glucose =13.3mmol/L; 16) History of repeated episodes of hypoglycemia in the past 3 months (more than 1 episode per week) or history of severe hypoglycemia; 17) Hyperlipidemia (TG > 5.6mmol/L) with a history of recurrent acute pancreatitis; 18) Mental illness that is unable to live independently or cooperate with treatment; 19) Blood glucose, body weight and body composition measurement and recording data are not allowed using blood glucose tester, body composition tester and other test equipment, or smart phones are not allowed; 20) The investigator believes that it is not suitable to participate in this study, or cannot cooperate with the 4-week intervention trial;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the change of Postprandial plasma glucose; | — |
Secondary
| Measure | Time frame |
|---|---|
| Glycated albumin;fast blood glucose;weight;percentage of body fat;HOMA-IR; | — |
Countries
the People's Republic of China
Contacts
Public ContactXiaohui Guo; Ziqian Li
Peking University First Hospital
Outcome results
None listed