lumbar disc herniation
Conditions
Interventions
The sequential method for designing a biased coin test group with a single arm.:Sequential design for titration of lumbar anesthesia concentration.
Optimal concentration group (O group):The lumbar anesthesia was administered based on the optimal concentration of ropivacaine determined by the initial test results
Conventional group (C group):The lumbar anesthesia was conducted using a standard concentration of ropivacaine(0.5%).
Sponsors
Ningbo No.6 Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. ASA grade I-II; 2. Age range of 18-70 years; 3. BMI between 18 and 35 kg/m2; 4. Patients opting for PELD and providing voluntary informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients with contraindications to excessive local anesthesia and epidural anesthesia; 2. Patients with severe systemic diseases, as well as those with intellectual disabilities or inability to communicate. 3. Other clinical trials are already in progress.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| VAS pain score; | — |
Secondary
| Measure | Time frame |
|---|---|
| ODI score;The monitoring of vital signs during surgery; | — |
Countries
China
Contacts
Public ContactLong Zhang
Ningbo No.6 Hospital
Outcome results
None listed