Carpal tunnel syndrome
Conditions
Interventions
5ml PRP:Inject 5mL PRP into the carpal tunnel
3ml PRP:Inject 3mL PRP into the carpal tunnel
Sponsors
The Sixth Affiliated Hospital of Sun Yat-sen University
Eligibility
Sex/Gender
All
Age
20 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) 20-80 years old; (2) patients diagnosed with moderate carpal tunnel syndrome according to electromyography; (3) carpal tunnel symptoms lasting for =1 month; (4) VAS numbness score =4 points (5) normal platelet count and coagulation function; (6) no long-term history of smoking or drinking; (7) without language or cognitive impairment; (8) voluntarily participate in this trial and sign informed consent.
Exclusion criteria
Exclusion criteria: (1) previous or planned wrist surgery within six months or previous history of severe wrist trauma; (2) patients who received any injection in carpal tunnel within the past 4 weeks; (3) serious skin damage or ulcers around the wrist; (4) patients with systemic use of corticosteroids in the past 2 weeks and non-steroidal anti-inflammatory drugs in the past 1 week; (5) patients who used anticoagulant or antiplatelet drugs in the past one month; (6) patients with diabetes, gout, metabolic, digestive tract, tumor, blood system and other basic diseases; (7) cervical spondylosis, brachial plexus disease, lateral epicondylitis, thoracic outlet syndrome, and other diseases; (8) pregnant and lactating women; (9) patients with hemoglobin <10g/L, platelet count < 150x10^9/L; (10) patients with a history of infectious diseases, eight tests of hepatitis B, HIV and syphilis were positive before operation; Recent febrile illness; (11) non-invasive contraindications or previous participation in similar experiments with carpal tunnel PRP injection.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| VAS score for numbness; | — |
Secondary
| Measure | Time frame |
|---|---|
| BCTQ-SSS;BCTQ-FSS;SNCV;DML;Cross sectional area of median nerve under ultrasound;Blood flow to the median nerve;Median nerve swelling rate; | — |
Countries
China
Contacts
Public ContactLi Jiang
The Sixth Affiliated Hospital of Sun Yat-sen University
Outcome results
None listed