Knee meniscus injury
Conditions
Interventions
Experimental group:Chitosan combined with platelet-rich plasma
Control group:Platelet-rich plasma
Sponsors
The General Hospital of Western Theater Command PLA
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Patients with meniscus injury confirmed by MRI classification (grade I ~ II) and grade III are not suitable for surgery; 2. Age 18-65 years old, gender unlimited; 3. Patients who intend to undergo intra-articular drug injection; 4. Patients without cognitive impairment who voluntarily participated in this study and signed informed consent;
Exclusion criteria
Exclusion criteria: 1. Infection at the injection site, as well as obvious swelling and fluid accumulation caused by other diseases cannot be ruled out This; 2. Patients with blood infection, abnormal coagulation function or undergoing anticoagulation therapy; 3. Patients with uncontrolled serious systemic diseases such as severe hepatic and renal insufficiency, hematological diseases or malignant neoplasms; 4. Hemoglobin content is less than 110 g/L and platelet content is less than 150×10*3 /L; 5. Pregnant and lactating women; 6. Patients with a recent history of knee arthroscopy or knee surgery on the affected joint; 7. People allergic to shrimp and crab; 8. Patients with contraindications in MRI examination (such as metal stents, etc.); 9 Any other circumstances in which the investigator considers it inappropriate to participate in the trial or for any reason not to cooperate with the study;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Knee injury and Osteoarthritis Outcome Score;Stoller grade of knee MRI; | — |
Secondary
| Measure | Time frame |
|---|---|
| VAS scale;IKDC scale;Incidence of complicatins; | — |
Countries
China
Contacts
Public ContactWu Wei
The General Hospital of Western Theater Command PLA
Outcome results
None listed