Pain after tibiofibular internal fixation
Conditions
Interventions
Ropivacaine group:Ultrasound guided saphenous nerve block: 10ml of 0.5% ropivacaine
Popliteal sciatic nerve block under ultrasound: 20ml of 0.5% ropivacaine.
Liposome bupivacaine group:Ultrasound guided saphenous nerve block: 10ml liposomal bupivacaine (89mg, 0.89%)
Ultrasound guided popliteal sciatic nerve block: 20ml (177mg, 0.89%) of liposome bupivacaine.
Sponsors
Zhejiang Xiaoshan Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: (1) ASA1-3 level; (2) age =18 years old, =65 years old;
Exclusion criteria
Exclusion criteria: Chronic pain syndrome, long-term use of opioid drugs (over 1 month), body mass index greater than 40kg/m2, allergic to investigational drugs, impaired cognitive function, contraindications to regional anesthesia, severe kidney disease (estimated glomerular filtration rate less than 50ml/min), congestive heart failure grade 3-4, severe liver disease, defined as current or past diagnosis of acute/subacute liver necrosis, acute liver failure, chronic liver disease, liver abscess, liver coma, hepatorenal syndrome, and other liver diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Duration of analgesia; | — |
Secondary
| Measure | Time frame |
|---|---|
| Dosage and parameters of sufentanil in analgesia pump 48h after surgery.;NRS pain scores (0-10) at rest and during activity were assessed every 4h for 72 hours after surgery.;Sensorimotor block was scored every 4h for 48h after surgery.;The patient's gender, age y, height cm, weight kg, ASA rating and other basic information were recorded.;Early activity time, hospital discharge date, and satisfaction score were recorded.;Adverse events such as patient falls, neurological damage, surgical infection, or accidental admission to the intensive care unit were recorded.; | — |
Countries
China
Contacts
Public ContactZhong Mei
Zhejiang Xiaoshan Hospital
Outcome results
None listed