Patients undergoing arthroscopic surgery under general anesthesia
Conditions
Interventions
Ciprofol group:In the Ciprofol group, general anesthesia was induced using ciprofol 0.2-0.4 mg/kg and sufentanil 0.3-0.5 µg/kg intravenously. Anesthesia was maintained with ciprofol 0.8-1.5 mg/kg/h
Propofol group:In the propofol group, general anesthesia was induced with propofol 2-3 mg/kg and sufentanil 0.3-0.5µg/kg intravenously. Anesthesia was maintained with propofol 4-10mg/kg/h.
Sponsors
Lishui People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Patients aged 18-65 years, ASA class 1-2, with a body mass index (BMI) =18 and =30 kg/m2; all patients who underwent arthroscopic surgery under general anesthesia were recruited.
Exclusion criteria
Exclusion criteria: 1. Pregnant or breastfeeding women and women who plan to give birth within 3 months (including male patients); 2. Obvious respiratory or circulatory dysfunction before surgery, obvious abnormalities in blood and biochemical indicators, serious neuropsychiatric disorders, endocrine system diseases, psychosomatic diseases, history of chronic analgesic or sedative drug use (including benzodiazepines), alcohol abuse, history of insomnia; 3. use of benzodiazepines or opioids within 1 month, contraindications to or allergic reactions to benzodiazepines, opioids, propofol, and their components; 4. those estimated to be difficult to intubate; 5. Patients who, in the judgment of the investigator, are not suitable for participation in this trial for any reason. Translated with www.DeepL.com/Translator (free version)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| QoR-15; | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality of sleep;MAP;HR;SPO2;Time from administration to loss of consciousness;Loss of consciousness BIS;Dose required for the loss of consciousness;Time from sedative medication to BIS60;Dose of sedative drugs to BIS60;Intraoperative use of vasoactive drugs;Low blood pressure;Blood pressure fluctuations;Cumulative dose of ciprofol or propofol;Cumulative dose of sufentanil;Cumulative dose of cisatracurium;Minimum intraoperative MAP;Minimum intraoperative HR;Records related to surgical anesthesia;Time from discontinuation to recovery of spontaneous respiration;Time to recovery of consciousness from drug withdrawal;Discontinue medication until consciousness is restored BIS;Time of extubation;Recovery room occupancy time;Orientation recovery time;Sedative agitation SAS score at Extubation;Time of discharging from bed;Total length of stay;Patient Satisfaction Score;Postoperative delirium; | — |
Countries
China
Contacts
Public ContactFaxing Wang
Lishui People's Hospital
Outcome results
None listed