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Effect and mechanism of vagus magnetic stimulation on upper limb motor function in ischemic stroke

Effect and mechanism of vagus magnetic stimulation on upper limb motor function in ischemic stroke

Status
Recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400082767
Enrollment
Unknown
Registered
2024-04-07
Start date
2023-03-23
Completion date
Unknown
Last updated
2024-04-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ischemic stroke

Interventions

VNM group:Vague nerve magnetic stimulation

Sponsors

The First Affiliated Hospital of Fujian Medical University, Fujian
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 80 Years

Inclusion criteria

Inclusion criteria: ? Patients with ischemic stroke aged 40-80 years; ? Chronic patients from 6 months to 5 years after ischemic stroke; ? Patients with moderate to severe upper limb mobility disorder were divided by FMA-UE score of 20-50. ? Agree to receive magnetic stimulation of vagus nerve and sign informed consent for treatment; ? Patients who can tolerate neuroregulatory tests and neurotransmitter function tests; ? Patients who agree to accept long-term follow-up.

Exclusion criteria

Exclusion criteria: ? Unstable vital signs; ? Intracranial malignancy or unruptured aneurysm; ? History of seizures or hydrocephalus; (4) Pregnancy; (5) Intracranial metal implantation or installation of cardiac pacemaker; ? Patients with severe cardiovascular, liver and kidney diseases; ? Other contraindications of peripheral magnetic stimulation.

Design outcomes

Primary

MeasureTime frame
Upper Limb Fugl-Meyer Assessment;functional near-infrared spectroscopy;motor evoked potential, MEP;

Secondary

MeasureTime frame
Wolf Motor Function Test,WMFT;Functional Independence Measure,FIM;Modified Ashworth Scale, MAS;

Countries

China

Contacts

Public ContactXiahua Liu

The First Affiliated Hospital of Fujian Medical University, Fujian

1014256630@qq.com+86 158 0603 8892

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026