Anti-acne
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1) 18-45 years old, regardless of gender; 2) Facial skin lesions, clinically diagnosed as Grade II acne patients (mainly manifested as acne and papules, with no more than 20 inflammatory skin lesions in the entire area); 3) The patient voluntarily participates in clinical observation and signs an informed consent form. They are willing to cooperate with follow-up observation and have good communication and understanding skills.
Exclusion criteria
Exclusion criteria: 1) Acne patients with pustules, cysts, or nodules on the face; 2) Use topical medications (such as retinoic acid) for treatment within two weeks; 3) Systemic treatment (oral antibiotics or retinoids) or physical and chemical therapy within one month; 4) There are other skin diseases in the affected area that may significantly affect the efficacy evaluation 5) Diseases related to female patients treated with estrogen or estrogen like hormones; 6) Individuals who suffer from severe allergic diseases or have had cosmetic allergies in the past 1-2 years; 7) Individuals with severe heart, brain, lung, liver, kidney function, and hematopoietic system disorders; 8) Pregnant women, breastfeeding or recently planned pregnancies (limited to females only); 9) Individuals with a history of psychological and mental illness, recent history of alcoholism or drug abuse; 10) Any other circumstances that the researcher deems unsuitable for participation in the trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Facial acne skin lesion count; | — |
Secondary
| Measure | Time frame |
|---|---|
| GAIS score;Porphyrin;Redness;Moisture content of stratum corneum;TEWL;Sebum;Security assessment;Acne-Specific Quality of Life Questionnaire; | — |
Countries
China
Contacts
West China Hospital, Sichuan University