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Clinical study on optimizing pulmonary ventilation and blood flow matching in ARDS based on EIT titration of optimal PEEP

Clinical study on optimizing pulmonary ventilation and blood flow matching in ARDS based on EIT titration of optimal PEEP

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400082748
Enrollment
Unknown
Registered
2024-04-07
Start date
2024-04-15
Completion date
Unknown
Last updated
2024-04-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute respiratory distress syndrome

Interventions

Intervention group A:During all study measurements, the ventilator settings of all patients were standardized, with tidal volume (Vt) ranging from 6-8 mL/kg ideal body weight and respiratory rate main
Intervention group B:During all study measurements, the ventilator settings of all patients were standardized, with tidal volume (Vt) ranging from 6-8 mL/kg ideal body weight and respiratory rate main
Intervention group C:During all study measurements, the ventilator settings of all patients were standardized, with tidal volume (Vt) ranging from 6-8 mL/kg ideal body weight and respiratory rate main

Sponsors

The Second Affiliated Hospital of Harbin Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: ? Age = 18 years old; ? Check in to the ICU; ? Meet the diagnostic criteria for ARDS defined in Berlin; ? Patients who receive mechanical ventilation through tracheal intubation or tracheostomy; ? The patient has a subclavian or jugular central venous catheter that is unobstructed and in place; ? The patient or their representative signs an informed consent form.

Exclusion criteria

Exclusion criteria: ? Hemodynamic instability (i.e. severe hypotension, despite fluid dilation and vascular activity support, systolic blood pressure180mmHg); ? There are contraindications to using EIT (such as the presence of a pacemaker or surgical wound on the chest)

Design outcomes

Primary

MeasureTime frame
Alveolar ventilation/pulmonary perfusion ratio;

Secondary

MeasureTime frame
Oxygenation index;Pulmonary static compliance;

Countries

China

Contacts

Public ContactWang Hongliang

The Second Affiliated Hospital of Harbin Medical University

icuwanghongliang@163.com+86 150 4537 7888

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026