Papillary carcinoma of thyroid
Conditions
Interventions
Thermal ablation Group (Retrospective study):NA
Thermal ablation Group (Prospective study):ultrasound-guided thermal ablation on T1-2N0M0 papillary thyroid carcinoma
Sponsors
First Affiliated Hospital of Dalian Medical University, Dalian, China
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) the cytological examination of fine needle aspiration biopsy or the pathological examination of thick needle aspiration biopsy before operation suggested that the primary papillary thyroid carcinoma (2) the tumor was confined to the thyroid gland, thyroid papillary carcinoma (T1-2N0M0) without invasion of thyroid capsule and surrounding tissues (3) patients without suspected metastatic lymph nodes or distant metastasis on imaging; (4) patients who could not tolerate or were unwilling to undergo surgery and who refused the clinical observer (patient requested minimally invasive intervention) and who agreed to participate in this clinical trial and voluntarily signed an informed consent form
Exclusion criteria
Exclusion criteria: 1. Invasion of the thyroid capsule and surrounding tissue, ultrasonography and CT scan showed the presence of regional lymph node or distant metastasis, which was confirmed by biopsy. 2. Non-papillary carcinoma was confirmed by biopsy. 3. Severe coagulation dysfunction or severe cardiopulmonary insufficiency.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The total absorption rate of the ablation at 12 months after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| Target lesion volume reduction rate 3 months after surgery;Target lesion volume reduction rate 6 months after surgery;Target lesion volume reduction rate 12 months after surgery;Rate of complete disappearance of target lesion after operation;Postoperative lymph node metastasis;Whether distant metastasis occurred after surgery; | — |
Countries
China
Contacts
Public ContactYing Che
The First Affiliated Hospital of Dalian Medical University
Outcome results
None listed