Nausea and vomiting caused by hyperemetic chemotherapy regimens
Conditions
Interventions
Case series:None
Sponsors
The First Affiliated Hospital of University of Science and Technology of China (Anhui Cancer Hospital)
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Male or female =18 years of age; 2. Patients with solid tumors requiring chemotherapy; 3. Plan a multi-day chemotherapy regimen with high emetic risk drugs; 4. Volunteer to participate in the study and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Allergic constitution or allergic to aprepitant or drug excipients; 2. Patients with difficulty in taking oral drugs; 3. Pregnant or lactating women; The subject (or her partner) plans a pregnancy within 3 months of the end of the study; 4. Suffering from a serious mental illness or mental disorder, unable to understand, read and complete the diary card filling; 5. Patients who have participated in other drug clinical trials within the last three months; 6. The investigator believes that the patient has other conditions that are not suitable for participation in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Complete response rate during the total observation period; | — |
Secondary
| Measure | Time frame |
|---|---|
| Complete response rate in acute phase;Complete control rate during the total observation period, acute phase, and delayed phase;Nausea relief rates during the total observation period, acute phase, and delayed phase;The proportion of subjects who did not use rescue therapy;The incidence of adverse events and adverse reactions; | — |
Countries
China
Contacts
Public ContactYueyin Pan
The First Affiliated Hospital of University of Science and Technology of China (Anhui Cancer Hospital)
Outcome results
None listed