Urinary tract stone
Conditions
Interventions
Ciprofol group:General anesthesia was induced with Ciprofol 0.2-0.4 mg/kg intravenously. Anesthesia was maintained with Ciprofol 0.8-1.5 mg/kg/h
Propofol group:In the propofol group, propofol 2-3mg/kg was used for induction of general anesthesia, and propofol 4-10mg/kg/h was used for maintenance of anesthesia.
Sponsors
Lishui People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Elective surgery, inpatients requiring ureteroscopy under general anesthesia tracheal intubation; 2. Male or female, age = 18 years and = 80 years; 3. American Society of Anesthesiologists (ASA) class I-III; 4. Body mass index (BMI) =18 and =30 kg/m2; 5. Vital signs during screening meet the following criteria: a) respiratory rate =10 and =24 breaths/min; b) arterial oxygen saturation (SpO2) =95% during respiration; c) systolic blood pressure =90 mmHg and =160 mmHg; d) diastolic blood pressure =60 mmHg and =100 mmHg; and e) heart rate =55 and =100 bpm.
Exclusion criteria
Exclusion criteria: 1. Pregnant or breastfeeding women and women who plan to give birth within 3 months (including male patients); 2. Obvious respiratory or circulatory dysfunction before surgery, obvious abnormalities in blood routine and biochemical indexes, and serious neuropsychiatric disorders; 3. Use of benzodiazepines or opioids within 1 month, contraindications or allergic reactions to benzodiazepines, opioids, propofol and its components; 4. Those estimated to be difficult to intubate; 5. Patients who, in the judgment of the investigator, are not suitable for participation in this trial for any reason.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| QoR-15 score; | — |
Secondary
| Measure | Time frame |
|---|---|
| MAP;The time it takes for consciousness to disappear;BIS value at loss of consciousness;Dose of medication required for loss of consciousness;Time to BIS 60;Drug dose required to BIS 60;Intraoperative vasoactive drug use;Lowest blood pressure after induction with ciprofol or propofol;Minimum intraoperative blood pressure and heart rate;Parameters related to surgical anesthesia;Lowest Heart Rate after induction with ciprofol or propofol;Minimum intraoperative heart rate;Time of discharging from bed;Patient Satisfaction Score;Urinary tract symptoms (urinary frequency, urgency, painful urination);Cumulative dose of propofol or cipofol administered;Cumulative dose of sufentanil;Cumulative dose of cisatracurium;Autonomous breathing recovery time;Recovery of consciousness time;Consciousness restoration BIS value;Tracheal tube extubation time;Recovery time inPACU;Recovery Phase RASS Scores;Total length of hospital stay; | — |
Countries
China
Contacts
Public ContactFaxing Wang
Lishui People's Hospital
Outcome results
None listed