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Inflammatory bowel disease associated gut microbiota change affects patients' cognitive function

Inflammatory bowel disease associated gut microbiota change affects patients' cognitive function

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400082730
Enrollment
Unknown
Registered
2024-04-07
Start date
2023-02-16
Completion date
Unknown
Last updated
2024-04-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

inflammatory bowel disease

Interventions

using biological agents:none

Sponsors

Second Affiliated Hospital of Army Medical University, ChongQing, China
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: (1) The age of the patient is 18 to 65 years old; (2) Have junior high school or above education level; (3) Clinical colonoscopy and pathological diagnosis of IBD active patients; (4) Have not used steroid drugs within 6 months; (5) Right-handed (5) Agree to participate in clinical research and sign informed consent;

Exclusion criteria

Exclusion criteria: (1) Those with endocrine, cardiovascular, liver and kidney, hyperthyroidism, hypertension, diabetes, rheumatoid arthritis and hematopoietic system, tumor or cancer and other related diseases that may affect cognition; (2) History of intestinal surgery, history of mental illness, history of taking anti-psychiatric drugs and history of alcohol abuse; (3) Previous encephalopathy surgery, brain trauma, and cerebral infarction; (4) The subject has metal and ferromagnetic substances in the body and is not suitable for magnetic resonance examination.

Design outcomes

Primary

MeasureTime frame
distribution of gut microbiota;MRI scan of the brain;

Secondary

MeasureTime frame
inflammatory factor in plasma;

Countries

China

Contacts

Public ContactXie Xia

Department of Gastroenterology, Second Affiliated Hospital of Army Medical University, ChongQing, China

xiexia0128@163.com+86 134 5216 6767

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026