Patients with gynecological diseases
Conditions
Interventions
Low dose of esketamine:0.25mg/kg esketamine
medium dose of esketamine:0.5mg/kg esketamine
control group:normal saline
Sponsors
Anhui Number 2 Province People's Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Age: 18 ~70 years old; BMI: 18~30kg/m2; ASA grade I~III; Laparoscopic gynecological surgery under elective general anesthesia; Volunteer to participate in the study and sign the informed consent.
Exclusion criteria
Exclusion criteria: Allergies to the drugs used in this study; Inability to communicate before surgery due to cognitive or language impairment; Heart, liver or kidney dysfunction; Untreated or poorly controlled high blood pressure; Glaucoma, elevated intracranial pressure, hyperthyroidism, or alcohol abuse; Esketamine contraindications (arteriosclerosis, coronary heart disease, cardiac insufficiency, pulmonary heart disease, pulmonary hypertension, etc.)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| postoperative quality of recovery score; | — |
Secondary
| Measure | Time frame |
|---|---|
| VAS;MAP;HR; | — |
Countries
China
Contacts
Public ContactLi Tingting
Anhui Number 2 Province People's Hospital
Outcome results
None listed