A comparation of efficacy and mechanism on accelerated continuous and intermittent theta burst stimulation for the treatment in depressive adolescents

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2400082708

Enrollment

Unknown

Registered

2024-04-04

Start date

2024-04-05

Completion date

Unknown

Last updated

2025-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Depressive adolescents

Interventions

a-cTBS group:Accelerated continuous TBS

a-iTBS group:Accelerated intermittent TBS

Eligibility

Sex/Gender

All

Age

12 Years to 18 Years

Inclusion criteria

Inclusion criteria: 1.Meets the diagnostic criteria for depressive disorders of the ICD-10; 2.Age 12-18 years; 3.Right-handed; 4.Signed an informed consent form;

Exclusion criteria

Exclusion criteria: 1.Participants with severe physical, infectious and immune system disorders; 2.Participants with severe neurological disorders, mental retardation or organic brain disorders; 3.Pregnant or breastfeeding women; 4.Participants who received electroconvulsive therapy within the last 3 months; 5.Participants with the history of seizures; 6.Participants who assessed to be unsuitable for cTBS treatment and those unable to complete relevant indicator collection;

Design outcomes

Primary

Measure	Time frame
HAMD;Suicidal ideation;	—

Secondary

Measure	Time frame
Neuroelectrophysiology and brain imaging;HAMA;Neuroinflammatory factors and related immune factors;	—

Countries

China

Contacts

Public ContactXiaoli Liu

The Affiliated Kangning Hospital of Ningbo University

1206207800@qq.com+86 574 26302510

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026