Functional dyspepsia syndrome in infants and toddler
Conditions
Interventions
Trial group:Partially hydrolysed protein lactose-reducing formula
Sponsors
Women and Children's Medical Center, Guangzhou Medical University
Eligibility
Sex/Gender
All
Age
No minimum to 0.5 Years
Inclusion criteria
Inclusion criteria: 1. 0-5 months of age, full-term, suitable for foetal age children 2. Exclusively artificially fed (i.e., on the day of the consultation, the parents of the subject confirmed that the child was exclusively artificially fed without the addition of any breast milk). 3. Functional dyspepsia syndrome in infants and toddler is diagnosed. 4. Formula selection is regular formula (non-special medical use formula) 5. Guardians voluntarily participate and sign an informed consent form.
Exclusion criteria
Exclusion criteria: 1. Parents did not consent to participate in the study; 2. Breastfeeding or mixed feeding children; 3. Are using other special medical formulas; 4. Have used or are using antibiotics and other supplements (probiotics, prebiotics, synbiotics, postbiotics) within 2 weeks; 5. Are using or have used gastrointestinal medications (PPIs, gastrointestinal motility medications, digestive enzymes, lactase, corticosteroids, proprietary medications for digestive discomfort, B and C vitamins, etc.) in the 7 days prior to the visit; 6. Presence of serious diseases (e.g., severe digestive, respiratory, neurological infections, other digestive diseases, anatomical abnormalities of the digestive tract, congenital malformations, growth retardation, etc.); 7. Presence of serious heart, brain, liver, kidney and haematopoietic system, connective tissue diseases, endocrine diseases, and psychiatric disorders; 8. Participation in other clinical studies within 12 weeks prior to screening; 9. Infants in whom organic diseases cannot be excluded for the time being.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Symptom score for functional dyspepsia syndrome in infants and toddler; | — |
Secondary
| Measure | Time frame |
|---|---|
| Fecal intestinal flora;calreticulin;Stool Acetic, Propionic and Butyric Acid Levels;sIgA;Symptom score for functional dyspepsia syndrome in infants and toddler;Rate of disappearance of individual symptoms;Weight;length; | — |
Countries
China
Contacts
Public ContactSitang Gong
Guangzhou Women and Children's Medical Center,Guangzhou Medical University
Outcome results
None listed