Head and neck squamous cell carcinoma
Conditions
Interventions
Dose reduction group - experimental group:Reduce the dose in the low-risk lymph node irradiation area of the neck to 40 Gy
Standard dose group - control group:Administer a dose of 50Gy to the low-risk lymph nodes in the neck area for radiation prevention
Sponsors
Anhui province Cancer Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1.Postoperative patients with head and neck squamous cell carcinoma confirmed by pathology. 2. Age = 18 years old. 3 KPS = 70. 4. Has not received head and neck radiation therapy in the past 5 has sufficient organ and bone marrow reserve function. 6. Neck CT and/or neck MRI examination is required.
Exclusion criteria
Exclusion criteria: 1.Clinical examination or imaging examination reveals the presence of distant metastasis. 2.Excluding second primary tumors other than nasopharyngeal and laryngeal cancers. 3. Have a history of invasive malignant tumors (excluding non melanoma skin cancer), unless there is no disease recurrence or progression for at least 1 year. 4. Previously received systemic chemotherapy treatment. 5. subjects did not receive any other investigational drugs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The rough risk of selective regional recurrence;MDADI;FACT-H&N; | — |
Secondary
| Measure | Time frame |
|---|---|
| Patient reported quality of life (QOL);RTOG/EORTC Radiation Damage Evaluation Criteria;PFS;OS;QLQ-H&N35; | — |
Countries
China
Contacts
Public Contactgao jin
Anhui provincial Cancer Hospital
Outcome results
None listed