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The mechanism of cerebral cortical hemodynamics regulated by rotation-traction manipulation in patients with cervical radiculopathy

Study on the dose-effect rule and hemodynamic mechanism of peripheral muscle-cerebral cortex of cervical radiculopathy treated by rotation-traction manipulation

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400082696
Enrollment
Unknown
Registered
2024-04-03
Start date
2024-04-15
Completion date
Unknown
Last updated
2024-04-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cervical radiculopathy

Interventions

Treatment group:Rotation-traction manipulation: The procedure for rotation-traction manipulation is as follows: The patient is seated, and their neck is allowed to relax. The physician applies massage
Control group:No treatment

Sponsors

Wangjing Hospital, China Academy of Chinese Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Treatment Group: (1) Conforming to the diagnostic criteria outlined in the 2010 North American Spine Society "An evidence-based clinical guideline for the diagnosis and treatment of cervical radiculopathy from degenerative disorders" (2) Aged 18 to 65; (3) Right-handed; (4) Normal vision (or corrected vision) and hearing without significant impairment; (5) No cognitive dysfunction, Mini-Mental State Examination (MMSE) score > 25 points; (6) Intact skull, no craniotomy or cranial bone repair surgery performed; (7) Voluntarily sign an informed consent form. Control Group: (1) Aged 18 to 65; (2) Right-handed; (3) No significant symptoms of neck discomfort; (4) Cervical X-ray film showing no "cervical degenerative changes" or "narrowing of intervertebral foramen"; (5) No significant neck disease confirmed by outpatient physicians; (6) Voluntarily sign an informed consent form.

Exclusion criteria

Exclusion criteria: (1) Concurrent with other types of cervical spondylosis; (2) Suspected or confirmed cases of cervical spine or intraspinal tumor, or intracranial tumor; (3) Patients with unclear diagnosis of spinal injury or symptoms of spinal cord injury; (4) Those with developmental spinal canal stenosis (vertebral canal ratio = sagittal diameter of vertebral canal / sagittal diameter of vertebral body < 0.75); (5) Patients with severe heart, lung, brain, liver, kidney, or hematopoietic system diseases; (6) Conditions such as skeletal tuberculosis, osteomyelitis, and osteoporosis; (7) Individuals who have undergone cervical spine surgery or have cervical spine deformities; (8) Pregnant, planning to become pregnant, or breastfeeding women; (9) Those unable to complete this clinical study due to mental illness, cognitive, or emotional disorders; (10) Participants in other clinical studies within the last 3 months.

Design outcomes

Primary

MeasureTime frame
Pain Visual Analog Scale;

Secondary

MeasureTime frame
Numbness Visual Analog Scale;Short Form 12-item Health Survey;The content of oxygenated hemoglobin and deoxygenated hemoglobin in cerebral cortex;Functional connection strength;Graph theory analysis: small world properties, clustering coefficient, shortest path length, global efficiency and local efficiency;

Countries

China

Contacts

Public ContactWei Xu

Wangjing Hospital, China Academy of Chinese Medical Sciences

weixu.007@163.com+86 134 8871 6557

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026