intestinal flora, skin status, glucose and lipid metabolism
Conditions
Interventions
Control group:Eat placebo (specifications per bottle: sodium alginate 1.0 g, rock sugar 3.7 g, water 65.3 g)
The bird's nest eating group:3.5 g / day edible bird 's nest (specification for each bottle: bird 's nest 3.5 g, rock sugar 3.7 g, water 62.8 g)
High-dose bird 's nest eating group:7 g / day edible bird 's nest ( 2 bottles, each bottle: bird 's nest 3.5 g, rock sugar 3.7 g, water 62.8 g)
Sponsors
Department of Nutrition and Food Hygiene, School of Public Health, Peking University
Eligibility
Sex/Gender
Female
Age
30 Years to 45 Years
Inclusion criteria
Inclusion criteria: a. Healthy or sub-healthy female subjects who volunteered to participate in this study, aged 30 to 45 years old. b. There is no intention or behavior ( such as changing skin care products or adjusting the frequency of using skin care products, etc. ) to deliberately change the skin care plan in the near future. c. No recent intentional change in lifestyle intentions or behavior ( such as diet or exercise to lose weight, etc. ). d. After screening, total cholesterol < 6.2mmol / L, low density lipoprotein cholesterol < 4.1mmol / L, fasting blood glucose < 7.0mmol / L, systolic blood pressure < 140mmHg, diastolic blood pressure < 90mmHg.
Exclusion criteria
Exclusion criteria: A. Patients with severe mental illness ( severe depression / dry depression, etc. ), severe sleep disorders, skin abnormalities ( such as spots, acne, tattoos, scars, erythema, telangiectasia or measurement of partial burn marks ) or other medical history that may affect the results of the study ; b. Those who are taking or taking health care products that may affect the results of the study, those who have received skin medical treatment in the past 6 months, and those who have participated in other skin health clinical researchers in the past 3 months ; c. Pregnant, lactating or pregnant women ; d. Persons allergic to bird 's nest.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Gut microbiota ;Fasting blood glucose;HgbA1C;Fasting insulin;Total cholesterol;Triglyceride;High Density Lipoprotein - Cholesterol ;Low Density Lipoprotein - Cholesterol ;Skin collagen density;Skin thickness;Skin elasticity;Skin moisture;Trans Epidermal Water Loss, TEWL;Facial skin condition; | — |
Secondary
| Measure | Time frame |
|---|---|
| Height;Weight;waistline;Blood pressure;Body composition;Uric acid;Urea nitrgen;Microglobulin;lgE;lgG;Complement C3;Complement C4;Complement c1q ;Alanine aminotransferase;Aspartate aminotransferase;High-sensitivity C-reactive protein;Serum sialic acid;Skin spots;Skin L*a*b*;Erythema index,EI;Skin grease;Skin melanin and whitening;pH;Physical activity;Food frequency;24h diet;Satiety, thirst, sleepiness, mood;Sleep quality;Depression;Anxiety; | — |
Countries
China
Contacts
Public ContactGuan Sheng Ma
Department of Nutrition and Food Hygiene, School of Public Health, Peking University
Outcome results
None listed