Regional anesthesia and pulmonary nodule
Conditions
Interventions
Group A:Intertransverse process block with 0.3 ml/kg of ropivacaine 0.375% ( contain 0.03 ml/kg (9 mg/kg) iodohydrin)
Group B:Intertransverse process block with 0.4 ml/kg of ropivacaine 0.375% ( contain 0.04 ml/kg (12 mg/kg) iodohydrin)
Group C:Intertransverse process block with 0.5 ml/kg of ropivacaine 0.375% ( contain 0.05 ml/kg (15 mg/kg) iodohydrin)
Sponsors
The First Affiliated Hospital of Gannan Medical College
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) American Society of Anesthesiologist physical status Classification I-II; (2) Patients aged 18-75 who plan to undergo computer tomography guided percutaneous localization or microwave ablation of pulmonary nodules; (3) Agree to participate in the study; (4) Can understand the relevant evaluation content; (5) BMI 18.5-28 kg/m2.
Exclusion criteria
Exclusion criteria: (1) Refusal to participate in research; (2) With severe comorbidities, including but not limited to renal dysfunction (creatinine>442) µmol/L or renal replacement therapy, liver dysfunction (Child Pugh C grade), and other serious cardiovascular and pulmonary diseases; (3) Contraindication of nerve block, including but not limited to be coagulation disorder, infection at the injection site, allergic to local anesthetic drug; (4) Allergic to contrast agents or other medications required for surgical procedures; (5) Individuals with anatomical abnormalities who are unable to undergo nerve block.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The distribution patterns of local anesthetics in nine predefined anatomical areas ( retro-superior costotransverse ligament space (RS); intervertebral foramen (IF); costotransverse space (CTS); erector spinae fascia (ESF); intercostal space (ICS); epidural space (ES); sympathetic ganglion (SG); lateral recess (LR); mediastinal compartments (MC) ); | — |
Secondary
| Measure | Time frame |
|---|---|
| Dermatomal distribution of sensory loss (after surgery); | — |
Countries
China
Contacts
Public ContactLifang Zhan
The First Affiliated Hospital of Gannan Medical College
Outcome results
None listed