painless gastroenteroscopy
Conditions
Interventions
Propofol group:For anesthetic induction, 0.1µg/kg of sufentanil and 1.5mg/kg of propofol were used. If the induced dose did not meet the adequate standard for sedation, 0.75 mg/kg of propofol was adde
Ciprofol group:For anesthetic induction, 0.1µg/kg sufentanil and 0.4mg/kg ciprofol were used. If the induced dose did not meet the adequate standard for sedation, 0.15 mg/kg ciprofol was added during
Sponsors
Xiangya Hospital, Central South University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Patients scheduled for gastroscopy; Age 18-65 years old; The ASA rating is I-III.
Exclusion criteria
Exclusion criteria: About to receive a tracheal tube or laryngeal mask; Recent use of sedatives or analgesics; A history of allergy to opioids, propofol, or ciprofol ingredients (e.g., soybean oil, glycerin, triglyceride, yolk lecithin, sodium oleate, and sodium hydroxide); Acute heart failure, unstable angina pectoris, myocardial infarction within 6 months prior to screening, resting electrocardiogram (ECG) heart rate <50 beats/min, grade III atrioventricular block, severe arrhythmia, moderate to severe heart valve disease; Have other severe respiratory diseases, such as acute respiratory infections, acute episodes of chronic obstructive pulmonary disease, uncontrolled asthma, etc.; Mental illness (schizophrenia, mania, bipolar disorder, mental disorder, etc.), long-term use of psychotropic substances, and cognitive impairment; Severe hepatic and renal insufficiency; Pregnancy or lactation; Participate in other clinical trials within the last 3 months; Patients undergoing gastroscopy combined with colonoscopy or gastroscopy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of quality dreams during sedation in both groups;Positive and negative emotional scores(PANAS) after awakening in both groups; | — |
Secondary
| Measure | Time frame |
|---|---|
| Sedation success rates in both groups;Vital signs and BIS data at time of administration (T1), time of adequate sedation/gastroscopy start (T2), time of examination completion (T3);Patient satisfaction score; | — |
Countries
China
Contacts
Public ContactZhong Tao
Xiangya Hospital, Central South University
Outcome results
None listed