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Comparison of diagnostic accuracy of contrast-enhanced ultrasound versus multiparameter MRI for the prediction of muscle-invasive bladder cancer:a prospective study

Comparison of diagnostic accuracy of contrast-enhanced ultrasound versus multiparameter MRI for the prediction of muscle-invasive bladder cancer:a prospective study

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400082646
Enrollment
Unknown
Registered
2024-04-02
Start date
2024-07-09
Completion date
Unknown
Last updated
2024-07-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

bladder cancer

Interventions

Gold Standard:the pathological specimens or findings that result from a medical procedure known as transurethral bladder resection (TURBT) or radical cystectomy
Index test:Contrast-enhanced ultrasound, Multiparameter MRI

Sponsors

Sun Yat-sen University Cancer Center
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1. Individuals aged 18 years or older. 2. Able to independently make decisions regarding diagnostic and therapeutic interventions, with the provision of obtaining informed consent signature. 3. Patients scheduled for total/partial cystectomy or transurethral resection, with availability of definitive postoperative pathology. 4.Patients undergoing contrast-enhanced ultrasound and MRI within two weeks after bladder lesion resection.

Exclusion criteria

Exclusion criteria: 1.Pregnant or breastfeeding women. 2.Patients in whom nodules cannot be visualized by either abdominal or endoscopic ultrasound. 3.Patients with contraindications for Doppler contrast-enhanced ultrasound. 4.Patients with contraindications for MRI. 5.Patients with unstable clinical condition, advanced disease, or unpredictable clinical course. 6.Patients who have received treatment for bladder lesions or those who have undergone cystoscopy within one week prior to ultrasound examination.

Design outcomes

Primary

MeasureTime frame
Sensitivity;Specificity;Area under the curve;

Countries

China

Contacts

Public ContactZhou Jianhua

Sun Yat-sen University Cancer Center

zhoujh@sysucc.org.cn+86 137 1175 7623

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026