valvulopathy
Conditions
Interventions
Group R:Transverse pectoralis combined with serratus anterior plane block
Group C:None
Sponsors
The First Affiliated Hospital of Hebei North University
Eligibility
Sex/Gender
All
Age
35 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Patients undergoing heart valve replacement under cardiopulmonary bypass (median thoracotomy); 2. American Society of Anesthesiology Classification I~III; 3. Age between 35 and 75 years old; 4. BMl between 18 and 30 kg/m2; 5. No myocardial infarction within the last 3 months; 6. No serious heart failure or malignant arrhythmia has occurred in the past; 7. Agree to participate in the study and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Those with heart valve replacement combined with coronary artery bypass surgery; 2. Those with secondary valve replacement; 3. Left ventricular ejection fraction=45%; 4. Those with preoperative dysfunction of liver,kidney,lung,brain,and blood coagulation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The amount of fentanyl used during surgery;Dosage of dioxacin for remedial analgesia after extubation;VAS score in resting state after extubation;VAS score in coughing state after extubation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Inflammatory factor(Levels of IL-6, IL-10 and TNF-a at different time points);Mean arterial pressure;Heart rate;First waking time after surgery;First postoperative extubation time; | — |
Countries
China
Contacts
Public ContactXingzhen
The First Affiliated Hospital of Hebei North University
Outcome results
None listed